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Frequently Asked Questions about Intrathecal Baclofen Therapy

What is Intrathecal Baclofen Therapy (ITB)?

Patients with severe spasticity that does not respond to other treatment options such as oral drugs(eg. Baclofen, dantrolene, benzodiazepines) or physical therapy may be treated with intrathecal baclofen. Baclofen is a medication that helps to relax muscles.

A baclofen pump is implanted in the lower abdomen and a small tube (catheter) is inserted through the skin and into the intrathecal space to deliver a constant, low dose of baclofen into the spinal cord. The pump is programmed to deliver baclofen continuously into the spinal cord to reduce muscle spasms and improve mobility. This system is inserted by a neurosurgeon after a successful baclofen trial.

Intrathecal baclofen therapy is not a cure for spasticity, but it can help manage the condition.

What is a baclofen trial?

A baclofen trial is a procedure in which a small amount of the medication baclofen is injected into the intrathecal space to test its effectiveness in reducing muscle spasticity.

This is done through a procedure called a lumbar puncture, also known as a spinal tap. A spinal needle is inserted into the lower back and into the spinal canal. Then, a trial dose of baclofen is injected into the intrathecal space and the patient is monitored for several hours to see if there is a reduction in muscle spasticity. If the trial is effective, a baclofen pump may be implanted by a neurosurgeon to deliver the medication continuously.

What are the benefits of Intrathecal Baclofen Therapy over traditional treatments?

Intrathecal baclofen therapy can offer several benefits over traditional treatments for spasticity, such as oral medications or physical therapy.

Potential benefits of intrathecal baclofen therapy include:

  1. Targeted treatment: By delivering the medication directly into the intrathecal space, intrathecal baclofen therapy can directly target the muscles that are causing the spasticity.

  1. Lower doses of medication: Because the medication is delivered directly into the spinal cord, lower doses of baclofen(micrograms) can be used compared to oral medications(milligrams), which can reduce the risk of side effects.

Overall, intrathecal baclofen therapy can be an effective treatment option for patients with severe spasticity that does not respond to other treatments.  Although intrathecal baclofen therapy does not cure spasticity, it can help to manage the condition and improve the patient’s quality of life.

What types of spasticity can baclofen pumps be used to treat?

Baclofen pumps can be used to treat a variety of spasticity types resulting from

  • traumatic brain injury (TBI),
  • spinal cord injury,
  • stroke,
  • multiple sclerosis (MS), or
  • cerebral palsy.